Fred D. Ledley, MD is the director of the Center for Integration of Science and Industry and a Professor in the Department of Natural and Applied Sciences and Department of Management and at Bentley University in Waltham, Mass. A recognized opinion leader in the integration of basic biological science with medicine, business, society, and education, he has written more than 170 papers and patent applications in fields ranging from molecular and human genetics and gene therapy to bioethics, biopharmaceutical development, and biotechnology. Ledley has served on the faculties of the Baylor College of Medicine and the Howard Hughes Medical Institute, and was involved in founding several biotechnology companies including GeneMedicine, Inc. and Variagenics Inc. in the area of gene therapy and personalized medicine, serving in roles ranging from VP R&D and CSO, to President & CEO. At Bentley, Ledley spearheaded strategic initiatives to reorganize and reorient the school’s science programs and better prepare business students for leadership roles in technology-driven enterprise. He serves as Chair of the National Biomedical Research Foundation and has served on the Board of Directors of the Massachusetts Biotechnology Council, the Board of Overseers of Boston Children’s Hospital, and as a consultant to industry, academia, and government. His research focuses on strategies for accelerating the translation of scientific discoveries for public benefit. He has a BS from the University of Maryland, an MD from Georgetown University, trained in Pediatrics and Genetics at the Children’s Hospital/Harvard Medical School, and was a post-doctoral fellow with Dr. David Baltimore at the Center for Cancer Research at MIT. View full bio.
Laura McNamee, PhD is a Research Associate in the Center for Integration of Science and Industry and Adjunct Assistant Professor of Natural and Applied Science. McNamee has a BS from Merrimack College and a PhD in Biomedical Sciences from the University of Massachusetts Medical School in Worcester where her work focused on experimental models of cancer cell death. As a post-doctoral fellow with Fred Ledley, she led projects looking at patterns of sustaining and disruptive innovation in biotechnology and examined technology metrics that contribute to effective business models within the biotech industry. McNamee is a member of Women Entrepreneurs in Science and Technology (WEST) and is active in the Science Club for Girls, an organization dedicated to promoting STEM education and careers for women. At Bentley, she teaches Human Biology.
Michael Boss, PhD, MBA is an Executive in Residence at the Center for Integration of Science and Industry at Bentley University. Boss has been a leader in the biotechnology industry for more than 30 years as a scientist and senior executive. As a group leader at Celltech, he was lead inventor of the landmark “Boss patent,” which enabled genetic engineering and manufacture of recombinant, monoclonal antibodies and generated >$1 billion in revenues. Dr. Boss co-founded Oros Instruments, a successful developer of protein purification equipment that was acquired by Biotage. He subsequently joined Genica Pharmaceuticals as Vice President of Research and Development and later Vice President of Operations, where he had a central role in building Genica (renamed Athena Diagnostics) into the leading developer of neurological and genetic tests. Most recently, Boss held the position of Vice President, Corporate Office of Technology, at Elan Corporation and Chief Operating Officer of Xanthus Pharmaceuticals Inc., leading its acquisition by Antisoma, where he continued in senior executive positions. He has a BSc and PhD from London University and an MBA from London Business School, trained in immunology at ICRF London with Dr. Mel Greaves and Dr. Martin Raff, and was a post-doctoral fellow with Dr. David Baltimore at the Center for Cancer Research at MIT.
Nancy Hsiung, PhD is an Executive in Residence at the Center for Integration of Science and Industry at Bentley University. She has more than 30 years of experience in the biotechnology industry, in both scientific and managerial positions as well as in the investment community. For the past 11 years, Hsiung worked with GeneChem Management Inc, a venture fund headquartered in Montreal, where her responsibilities included sourcing, assessing and managing investment opportunities. Prior to GeneChem, Nancy was a consultant whose activities range from strategic planning, business development, technology assessment, market research and financing for biotechnology and biopharmaceutical companies. She started her career on the operational side as a scientist with Integrated Genetics (now part of Genzyme, now Sanofi) where she established the company's gene expression and tissue culture capabilities, as a member of the management team at Applied Biotechnology, whose focus was on vaccines and oncology and as the U.S. head of Corporate Development for Toyobo Corporation's (a large Japanese multinational) biopharmaceutical division. Hsiung received a BA degree from the University of Pennsylvania and a PhD degree in chemistry from Columbia University; she completed her post-doctoral studies in molecular biology at Yale University and Princeton University. She holds more than 15 patents and patent applications worldwide and has written 12 publications/abstracts.
Michael Jay Walsh, PhD is a Post-doctoral Research Fellow at the Center for Integration of Science and Industry. Walsh holds a BA in Chemistry from Colby College where he researched lake water eutrophication and the marine chemistry of iron and superoxide. He obtained a PhD in the field of Environmental Engineering from Cornell University where his work focused on the effect of thiols on the bioavailability of copper to marine algae. While at Cornell, Walsh served as a member of the President’s Climate Commitment Implementation and Sustainable Campus Committees and was elected by the student body to serve on the University’s Board of Trustees. He has received awards from the New York State Water Environment Association and the American Institute of Biological Sciences for his work at the science & policy interface. At the Center, Walsh will research the development of energy and sustainable technologies.
Jennifer Beierlein, PhD is a Post-doctoral Research Fellow at the Center for Integration of Science and Industry. Beierlein holds a BS in Biochemistry from Russell Sage College. She obtained her PhD in Medicinal Chemistry from the University of Connecticut in 2011, where her research project explored antibiotic drug discovery targeting Anthrax infections. She then joined Brandeis University as a Ruth L. Kirschstein research fellow studying neurodegenerative diseases using yeast as a model organism. During her studies, she has taken an active interest in science policy, including participating in meetings on Capitol Hill and attending AAAS national meetings. At the Center, she will utilize business and technology metrics to research the factors involved in neurodegenerative disease therapeutic development.
Current Undergraduate Researchers
Cory Kalin ‘15
JR Brennan ‘15
Rachel Spero '15
Usama Salim '17
Jake Wegweiser '17
Peter Connolly '14
Ryan Belleville, U MA Lowell '16
Quinyi "Agnes" Xu, '15
Ashley Rossi ‘13
Aaron Perlman '13
Katie DiTomaso ‘13
Eric Ndung’u ‘12
Vedat Uzdil ‘11