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Center for Integration of Science and Industry


Center for Integration of Science and Industry

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The mission of the Center for Integration of Science and Industry is to "understand the process by which science is translated for public value, and accelerate this translation by engaging science and industry in interdisciplinary dialogue, scholarship, and education."

The Center brings together the perspectives of natural science, business, analytics, and policy to understand, and advance, the path of translational science and the business models that create public value from the fruits of scientific discovery.

Dr. Fred Ledley
Bentley's Center for Integration of Science and Industry is pretty unique. It's a research center at a school that has both a great business tradition and a great science department and our role is really to try to bring that together.
Dr. Fred Ledley
Director, Center for Integration of Science and Industry

Research & News

Research spending on new drug approvals by NIH vs industry

Our recent study shows NIH investment in new drug approvals is comparable to investment by the pharmaceutical industry. 

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Dr. Lawrence Tabak references our work in his testimony

Dr. Lawrence Tabak, Director of the National Institutes of Health states, "An independent analysis by researchers at Bentley University found that NIH funding contributed to development of every new drug, all 356, approved by the FDA from 2010-2019." (43:46)


Economic terms of biotech licenses from academic institutions vs between commercial firms

Our recent study shows the disparity between returns from public and private sector investment in biomedical science. This work was based on Prateet Shah '20's Honors Capstone Project, for which he received Bentley's "Best Capstone in Arts & Sciences" award.

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Reforming the Business of Pharmaceutical Innovation

A series of workshops March 16-18, 2021 explored the public value created from public and private investments in pharmaceutical innovation and identified unanswered questions about the roles of science, business, and policy.

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Alexandria Ocasio-Cortez Stands Up to Big Pharma

Representative Alexandria Ocasio-Cortez uses information from the Center for Integration of Science and Industry's PNAS paper.

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Can big pharma afford to reduce drug prices?

For years, biopharmaceutical companies have argued that reducing consumer costs would compromise their ability to discover and develop additional products. However, Fred Ledley and Gregory Vaughan dispelled this “innovation myth” in the Center's latest research.

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Research Highlights

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Contribution of NIH funding to new drug approvals 2010–2016

View continuously updated attention metrics for article published in Proceedings of the National Academy of Sciences of the United States of America, February 2018.


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Congressional Testimony

At a September 27, 2019 hearing of the House Appropriations Subcommittee on Labor, Health and Human Services, Education and Related Agencies, Representative Mark Pocan (D-WI) asked the Director of the NIH, Dr. Francis Collins, if the Center for Integration of Science and Industry was planning to repeat the landmark 2018 study, published in the Proceedings of the National Academy of Sciences, establishing that NIH funding contributed to every new drug approved by the FDA from 2010-2016. Researchers at the Center are currently working on extending this analysis, a project that will be completed in spring 2020."
Here is the link to the "landmark 2018 study":

Interactive Dashboards

Impact of Drug Price on Pipeline of New Drug Launches

Enables you to model the impact of drug price reductions of 0-20% with differential allocation of cost reductions through phased clinical development.

Learn About the Center

"Professor Ledley discovered that there was a large disconnect between the business people and biotech companies, as well as the scientist, where the businessmen didn't understand the science and the scientists don't understand the business."

- JR Brennan '15, former undergraduate research assistant


Student Alumni Spotlight

Rachel Spero, '15

Rachel Spero, '15

"After graduating from Bentley, I went on to earn my Master’s Degree in Public Administration from Northeastern University. While in graduate school, I worked in Development for a non-profit homeless shelter in Dorchester, St. Mary’s Center for Women and Children. Currently, I work as a Research Analyst for the Lowell Housing Authority where I use operational research methods and cost benefit analysis to identify improvement areas throughout the agency. I interpret data and devise and implement recommendations to reduce agency costs, increase revenues, and improve service delivery. ... "

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Contact Us

         Location: Jennison 143                 Telephone: (781) 891-2984                 Email: