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Center for Integration of Science and Industry


Center for Integration of Science and Industry

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The mission of the Center for Integration of Science and Industry is to "understand the process by which science is translated for public value, and accelerate this translation by engaging science and industry in interdisciplinary dialogue, scholarship, and education."

The Center brings together the perspectives of natural science, business, analytics, and policy to understand, and advance, the path of translational science and the business models that create public value from the fruits of scientific discovery.

Dr. Fred Ledley
Bentley's Center for Integration of Science and Industry is pretty unique. It's a research center at a school that has both a great business tradition and a great science department and our role is really to try to bring that together.
Dr. Fred Ledley
Director, Center for Integration of Science and Industry

Research & News

Association between expedited review designations and the US or global burden of disease

Our recent study shows that expedited approval programs may disincentivize development of drugs for conditions associated with the greatest burden of disease.

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Considering returns on federal investment in negotiated “maximum fair price” of drugs under IRA

Our recent study shows that the NIH spent $11.7 billion on research leading to approval of drugs selected for price negotiations in year one of the Inflation Reduction Act.

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The White House references our work in statement

Biden-Harris Administration announces new actions to lower health care and prescription drug costs while citing our working paper

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Research spending on new drug approvals by NIH vs industry

Our recent study shows NIH investment in new drug approvals is comparable to investment by the pharmaceutical industry. 

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Dr. Lawrence Tabak references our work in his testimony

Dr. Lawrence Tabak, Director of the NIH states, "An independent analysis by researchers at Bentley University found that NIH funding contributed to development of every new drug, all 356, approved by the FDA from 2010-2019." (43:46)


Do biotech licenses from academic institutions have reasonable royalty rates?

Our recent study shows the disparity between returns from public and private sector investment in biomedical science. This work was based on Prateet Shah '20's Honors Capstone Project, for which he received Bentley's "Best Capstone in Arts & Sciences" award.

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Research Highlights

Congressional Testimony

At a September 25, 2019 hearing of the House Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies, Representative Mark Pocan asked Dr. Francis Collins, Director of the NIH, if the Center for Integration of Science and Industry was planning to expand on the 2018 study, published in PNAS, establishing that NIH funding contributed to every new drug approved by the FDA from 2010-2016. Researchers at the Center extended this analysis through 2019 in a 2020 working paper published by INET.

Watch Full Testimony


Alexandria Ocasio-Cortez Stands Up to Big Pharma

Representative Alexandria Ocasio-Cortez uses information from the Center for Integration of Science and Industry's PNAS paper.


Interactive Dashboards

Impact of Drug Price on Pipeline of New Drug Launches

Enables you to model the impact of drug price reductions of 0-20% with differential allocation of cost reductions through phased clinical development.

Student Alumni Spotlight

Sarah Al-Masri '22

Sarah Al-Masri '22

"I remember applying to the Center of Integration of Science and Industry during the winter break of my Junior year (December 2020). It was during the height of the pandemic when I was doing all of my classes online. During that time, I realized I wanted to pursue a career in research and academia, so I was excited to see a listing for a Research Assistantship at CISI. The year I spent working at the Center was an incredibly memorable year and one that gave me so much experience to be able to continue doing research in this field. ..."

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Contact Us

         Location: Jennison 143  |  Telephone: (781) 891-2984  |  Email: